.share{padding:24px 0}.share_inner{justify-content:space-between;align-items:center;display:flex}@media (max-width:1080px){.share_inner{flex-direction:column;align-items:flex-start;gap:24px}}@media (max-width:767px){.share_inner{gap:10px}}.share_right{justify-content:space-between;align-items:center;gap:32px;display:flex}@media (max-width:767px){.share_right{flex-direction:column;align-items:flex-start;gap:16px}}.share_social{flex-wrap:wrap;justify-content:space-between;align-items:center;gap:24px;display:flex}@media (max-width:767px){.share_social{gap:20px}}.share_social-icons{align-items:center;gap:24px;display:flex}@media (max-width:767px){.share_social-icons{gap:8px}}.share_right-separator{width:1px;height:48px}@media (max-width:767px){.share_right-separator{display:none}}.share_print{justify-content:space-between;align-items:center;gap:24px;display:flex}@media (max-width:767px){.share_print{gap:16px}}.share_icon{will-change:background-color,border-color;border-style:solid;border-width:1px;justify-content:center;align-items:center;width:48px;height:48px;transition:background-color .2s,border-color .2s,color .2s;display:flex}.share_icon svg{width:24px;height:24px}.share_icon svg path{will-change:fill;transition:fill .2s}@media (max-width:767px){.share_icon{width:40px;height:40px}.share_icon svg{width:20px;height:20px}}@media (max-width:480px){.share_icon{width:36px;height:36px}.share_icon svg{width:20px;height:20px}}
.pagination-form{align-items:center;display:flex}.pagination-form_label{margin-right:16px}@media (max-width:420px){.pagination-form_label{margin-right:8px}}
.pagination-wrapper{justify-content:center;align-items:center;gap:64px;display:flex}@media (max-width:768px){.pagination-wrapper{flex-direction:column;gap:24px}}@media (max-width:420px){.pagination-wrapper{gap:16px}}.pagination{justify-content:center;align-items:center;gap:16px;display:flex}.pagination li a{cursor:pointer;justify-content:center;align-items:center;width:auto;min-width:24px;height:24px;display:inline-flex}.pagination li a[aria-disabled=true]{cursor:default}@media (max-width:420px){.pagination{gap:6px}}.pagination-info{display:none}
.trial-results_cards{flex-direction:column;gap:24px;display:flex}.trial-results_card{justify-content:space-between;align-items:center;display:flex}@media (max-width:400px){.trial-results_card{flex-direction:column;align-items:flex-start;gap:16px}}.trial-results_card-title{margin-bottom:4px}.trial-results_modal-checkboxes{flex-wrap:wrap;gap:16px;display:flex}.trial-results_modal-checkboxes .radio-group_items{flex-flow:wrap}
.radio-group_label{margin-bottom:16px}.radio-group_items{flex-direction:column;align-items:flex-start;gap:16px;display:flex}.radio{cursor:pointer;align-items:center;display:flex}.radio_input{cursor:pointer;display:none}.radio_button{will-change:background-color,box-shadow,border-color;border-radius:50%;justify-content:center;align-items:center;width:20px;min-width:20px;height:20px;transition:background-color .2s,box-shadow .2s,border-color .2s;display:flex}.radio_button:after{content:"";border-radius:50%;width:12px;height:12px;transition:transform .2s;transform:scale(0)}.radio_label{padding-left:12px}.radio-group_error{margin-top:12px}
.dot-spinner{--uib-speed:.9s;justify-content:flex-start;align-items:center;width:2.8rem;height:2.8rem;display:flex;position:relative}.dot-spinner_dot{justify-content:flex-start;align-items:center;width:100%;height:100%;display:flex;position:absolute;top:0;left:0}.dot-spinner_dot:before{content:"";opacity:.5;width:20%;height:20%;animation:pulse0112 calc(var(--uib-speed)*1.111)ease-in-out infinite;border-radius:50%;transform:scale(0);box-shadow:0 0 20px #121f354d}.dot-spinner_dot:nth-child(2){transform:rotate(45deg)}.dot-spinner_dot:nth-child(2):before{animation-delay:calc(var(--uib-speed)*-.875)}.dot-spinner_dot:nth-child(3){transform:rotate(90deg)}.dot-spinner_dot:nth-child(3):before{animation-delay:calc(var(--uib-speed)*-.75)}.dot-spinner_dot:nth-child(4){transform:rotate(135deg)}.dot-spinner_dot:nth-child(4):before{animation-delay:calc(var(--uib-speed)*-.625)}.dot-spinner_dot:nth-child(5){transform:rotate(180deg)}.dot-spinner_dot:nth-child(5):before{animation-delay:calc(var(--uib-speed)*-.5)}.dot-spinner_dot:nth-child(6){transform:rotate(225deg)}.dot-spinner_dot:nth-child(6):before{animation-delay:calc(var(--uib-speed)*-.375)}.dot-spinner_dot:nth-child(7){transform:rotate(270deg)}.dot-spinner_dot:nth-child(7):before{animation-delay:calc(var(--uib-speed)*-.25)}.dot-spinner_dot:nth-child(8){transform:rotate(315deg)}.dot-spinner_dot:nth-child(8):before{animation-delay:calc(var(--uib-speed)*-.125)}@keyframes pulse0112{0%,to{opacity:.5;transform:scale(0)}50%{opacity:1;transform:scale(1)}}
.multi-select{flex-direction:column;gap:8px;display:flex}.multi-select.is-opened .multi-select_dropdown{opacity:1;visibility:visible}.multi-select.is-opened .multi-select_button svg{transform:rotate(180deg)}.multi-select_label{position:relative}.is-required .multi-select_label:after{content:"*";margin-left:2px;display:inline-block;position:relative}.multi-select_box{position:relative}.multi-select_input-wrapper{align-items:center;width:100%;display:flex;position:relative}.multi-select_input{cursor:text;flex-wrap:wrap;gap:8px;width:100%;min-height:40px;display:flex}.multi-select_input[data-disabled=true]{cursor:default;opacity:.5}.multi-select_selected-item{align-items:center;gap:8px;display:inline-flex}.multi-select_clear-item{cursor:pointer;background-color:#0000;border:none;width:12px;height:12px}.multi-select_clear-item svg{width:12px;height:12px}.multi-select_dropdown{visibility:hidden;opacity:0;width:100%;position:absolute;top:100%;left:0}.multi-select_button{background-color:#0000;border:none;justify-content:center;align-items:center;display:flex;position:absolute;top:20px;right:12px;transform:translateY(-50%)}.multi-select_button svg{width:20px;height:20px}.multi-select_button:disabled{opacity:.5}.multi-select_item{cursor:pointer;align-items:center;gap:8px;display:flex}
.footer-otsuka{padding:64px 0 110px;position:relative}@media (max-width:767px){.footer-otsuka{padding:150px 0 60px}}.footer-otsuka_top{margin-bottom:64px}@media (max-width:767px){.footer-otsuka_top{margin-bottom:55px}}.footer-otsuka_middle{gap:32px;margin-bottom:64px;display:flex}@media (max-width:767px){.footer-otsuka_middle{flex-direction:column;margin-bottom:55px}}.footer-otsuka_middle-left{width:calc(50% - 16px);display:flex}@media (max-width:767px){.footer-otsuka_middle-left{flex-direction:column;gap:48px;width:100%}}.footer-otsuka_social-media{width:50%}@media (max-width:767px){.footer-otsuka_social-media{width:100%}}.footer-otsuka_social-media-title{margin-bottom:24px;padding-bottom:10px}.footer-otsuka_navigation{width:50%}@media (max-width:767px){.footer-otsuka_navigation{width:100%}}.footer-otsuka_locations{width:calc(50% - 16px)}@media (max-width:767px){.footer-otsuka_locations{width:100%}}.footer-otsuka_locations-title{margin-bottom:24px;padding-bottom:10px}.footer-otsuka_locations-list{flex-wrap:wrap;gap:32px 0;display:flex}@media (max-width:1024px){.footer-otsuka_locations-list{flex-direction:column}}@media (max-width:767px){.footer-otsuka_locations-list{gap:22px}}.footer-otsuka_locations-item{width:50%}@media (max-width:1024px){.footer-otsuka_locations-item{width:100%}}.footer-otsuka_bottom{justify-content:space-between;align-items:flex-end;display:flex}@media (max-width:767px){.footer-otsuka_bottom{flex-direction:column;align-items:flex-start;gap:24px}}.footer-otsuka_bottom-right{align-items:center;gap:20px;display:flex}@media (max-width:767px){.footer-otsuka_bottom-right{flex-direction:column;gap:0}}
.footer{position:relative}.footer_top{padding:48px 0 28px}@media (max-width:420px){.footer_top{padding:20px 0 24px}}.footer_top-inner{justify-content:space-between;align-items:center;display:flex}@media (max-width:1300px){.footer_top-inner{flex-direction:column;gap:24px}}.footer_top-left{flex-direction:column;display:flex}.footer_top-right{flex-direction:column;align-items:flex-end;display:flex}@media (max-width:1300px){.footer_top-right{align-items:center}}.footer_disclaimer{margin-top:12px}@media (max-width:1300px){.footer_disclaimer br{display:none}}.footer_navigation-list{align-items:center;gap:24px;display:flex}@media (max-width:1300px){.footer_navigation-list{flex-direction:column;gap:14px}}@media (max-width:420px){.footer_navigation-list{gap:8px}}.footer_social-list{align-items:center;gap:10px;margin-top:32px;display:flex}@media (max-width:1300px){.footer_social-list{justify-content:center}}.footer_social-link svg{width:20px;height:20px}.footer_top-citeline{align-items:center;gap:8px;display:flex}
.accordion-tabs_main{gap:64px;display:flex}.accordion-tabs_main[data-tabs-position=right]{flex-direction:row-reverse}.accordion-tabs_left{flex-direction:column;gap:16px;width:280px;display:flex}@media (max-width:767px){.accordion-tabs_left{width:100%}}.accordion-tab[data-opened=is-opened] .accordion-tab_content{grid-template-rows:1fr}.accordion-tab_top{cursor:pointer;padding:8px 24px;transition:background-color .3s}.accordion-tab_title{transition:color .3s}.accordion-tab_content{display:none}@media (max-width:767px){.accordion-tab_content{grid-template-rows:0fr;transition:grid-template-rows .3s;display:grid}}.accordion-tab_content-inner{padding:16px}@media (max-width:767px){.accordion-tab_content-inner{padding:0 16px;overflow:hidden}.accordion-tab_content-inner .rich-text{padding:16px 0}.accordion-tabs_right{display:none}}.accordion-tabs_right-title{margin-bottom:16px}.accordion-tab_index{display:none}
.banner{z-index:1;background-position:50%;background-size:cover;padding:128px 0;position:relative}@media (max-width:1200px){.banner{padding:88px 0}}@media (max-width:767px){.banner{padding:66px 0}}.banner_inner{flex-direction:column;gap:24px;display:flex}.banner-links-selector{display:none}.gsk .banner--sitemap{color:#fff;background-color:#f36633;padding:64px 0}@media (max-width:767px){.gsk .banner--sitemap{padding:40px 0}}.gsk .banner--sitemap .rich-text h1{margin-bottom:24px;font-size:40px;font-weight:700;line-height:56px}@media (max-width:767px){.gsk .banner--sitemap .rich-text h1{margin-bottom:16px}}.gsk .banner--sitemap .rich-text p{margin-bottom:0;font-size:20px;font-weight:300;line-height:28px}
.cards_cards{gap:32px;display:flex}.cards_content{margin-bottom:32px}.cards_bottom-content{margin-top:32px}.cards_card{flex:1;text-decoration:none;display:flex}.cards_card.vertical{flex-direction:column}.cards_card.horizontal{flex-direction:row}.cards_card-left{overflow:hidden}.cards_card-image{object-fit:cover;object-position:center;width:100%;height:240px;display:block}.cards_card-right{flex-direction:column;flex:1;align-items:flex-start;padding:24px;display:flex}.cards_card-link-group{margin-top:auto}.card_card-content{text-decoration:none}.card_card-content .rich-text{margin-bottom:16px}.card_card-content h3{margin-bottom:8px}.card_card-content p{margin-bottom:16px}.cards_card-index{display:none}
.chatbot_inner{min-width:75%}.chatbot{gap:2rem;width:100%;display:grid}.chatbot__header{gap:1rem;width:100%;display:grid}.chatbot__title{margin:0}.chatbot__intro{color:var(--text-color,inherit)}.chatbot__error{background:#ad31310f;border:1px solid #ad313133;border-radius:1rem;padding:1rem 1.25rem}.chatbot__error strong,.chatbot__error p{margin:0;display:block}.chatbot__error p{margin-top:.4rem}.chatbot__shell{background:#fff;border:1px solid #11182714;border-radius:1.5rem;width:100%;overflow:hidden}.chatbot__results-title{color:#334155;padding:1rem 1.5rem 0;font-size:.95rem;font-weight:700}.chatbot__messages{background:radial-gradient(circle at 0 0,#2684ff14,#0000 28%),linear-gradient(#f5f7fad9,#fffffffa);gap:1rem;width:100%;min-height:22rem;max-height:34rem;padding:1.5rem;display:grid;overflow-y:auto}.chatbot__message{align-items:flex-start;display:flex}.chatbot__message--assistant{justify-content:flex-start}.chatbot__message--user{justify-content:flex-end}.chatbot__bubble{white-space:pre-wrap;border-radius:1.25rem;align-self:flex-start;max-width:min(44rem,88%);padding:.9rem 1rem;line-height:1.5;display:inline-block;box-shadow:0 .75rem 2rem #0f172a0f}.chatbot__message--assistant .chatbot__bubble{color:#0f172a;background:#fff;border-top-left-radius:.4rem}.chatbot__message--user .chatbot__bubble{color:#fff;background:#0f172a;border-top-right-radius:.4rem}.chatbot__bubble--loading{align-items:center;gap:.45rem;min-width:4rem;display:inline-flex}.chatbot__options{flex-wrap:wrap;gap:.65rem;margin-top:.9rem;display:flex}.chatbot__option{color:#0f172a;cursor:pointer;background:#f8fafc;border:1px solid #0f172a1f;border-radius:999px;padding:.55rem .9rem;transition:background-color .2s,border-color .2s}.chatbot__option:hover:not(:disabled){background:#eef2ff;border-color:#0f172a38}.chatbot__option:disabled{opacity:.5;cursor:not-allowed}.chatbot__dot{background:#475569;border-radius:999px;width:.5rem;height:.5rem;animation:1s ease-in-out infinite chatbot-dot}.chatbot__dot:nth-child(2){animation-delay:.15s}.chatbot__dot:nth-child(3){animation-delay:.3s}.chatbot__composer{background:#fff;border-top:1px solid #11182714;grid-template-columns:1fr auto;gap:.75rem;width:100%;padding:1rem;display:grid}.chatbot__input{color:#0f172a;background:#fff;border:1px solid #0f172a1f;border-radius:999px;width:100%;padding:.9rem 1rem}.chatbot__submit{color:#fff;cursor:pointer;background:#0f172a;border:0;border-radius:999px;padding:.9rem 1.25rem}.chatbot__submit:disabled{opacity:.5;cursor:not-allowed}.chatbot__empty{color:#64748b;text-align:center;place-self:center}.chatbot__sr-only{clip:rect(0,0,0,0);white-space:nowrap;border:0;width:1px;height:1px;margin:-1px;padding:0;position:absolute;overflow:hidden}@keyframes chatbot-dot{0%,80%,to{opacity:.35;transform:translateY(0)}40%{opacity:1;transform:translateY(-.12rem)}}