Study summary

The purpose of the study was to evaluate the efficacy of ASP0113 compared with placebo as measured by a primary composite endpoint of overall mortality and CMV end organ disease (EOD) through 1 year post-transplant. Safety of ASP0113 in participants undergoing allogeneic HCT will also be evaluated.

Additional Study Details

Phase
Phase 3
Product
ASP0113
Product
Placebo
Type
Interventional
Masking
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Enrollment number
514
Show Additional Study Details

Study documents

Protocol
Available Language(s): English, English
Statistical Analysis Plan (SAP)
Available Language(s): English, English
Plain Language Summary
Available Language(s): English

Get more information

Would you like more information about clinical trial sites that are recruiting participants for A Study to Evaluate a Therapeutic Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seropositive Recipients Undergoing Allogeneic, Hematopoietic Cell Transplant (HCT)? Contact us by filling out your information to the right and we’ll respond to you.

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  • Algeria
  • Argentina
  • Armenia
  • Australia
  • Austria
  • Belarus
  • Belgium
  • Bosnia And Herzegovina
  • Brazil
  • Bulgaria
  • Canada
  • Chile
  • China
  • Colombia
  • Croatia
  • Czech Republic
  • Denmark
  • Dominican Republic
  • Egypt
  • Estonia
  • Finland
  • Former Serbia and Montenegro
  • France
  • Georgia
  • Germany
  • Greece
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  • Hong Kong
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  • Iceland
  • India
  • Indonesia
  • Ireland
  • Israel
  • Italy
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  • Ukraine
  • United Kingdom
  • United States
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    Locations

    Contact Us
    Contact Us
    Completed
    Site JP81001
    Fukuoka, Fukuoka, Japan
    Active, not recruiting
    Site US10036
    Rochester, MN, United States, 55905
    Active, not recruiting
    Site US10024
    Seattle, WA, United States, 98109
    Completed
    Site JP81003
    Nagoya, Aichi, Japan
    Withdrawn
    Site DE49003
    Wiesbaden, Germany, 65191
    Withdrawn
    Site US10029
    Winston-Salem, NC, United States, 27157
    Active, not recruiting
    Site US10025
    Chapel Hill, NC, United States, 27514
    Completed
    Site JP81005
    Fukuoka, Fukuoka, Japan
    Completed
    Site KR82004
    Seoul, Seoul Teugbyeolsi, Republic of Korea, 06351
    Completed
    Site FR33010
    Nice, France, 06200
    Active, not recruiting
    Site US10039
    Seattle, WA, United States, 98108
    Completed
    Site KR82003
    Seoul, Republic of Korea, 110744
    Active, not recruiting
    Site BE32005
    Leuven, Belgium, 3000
    Completed
    Site JP81009
    Minato-ku, Tokyo, Japan
    Active, not recruiting
    Site US10028
    Birmingham, AL, United States, 35294
    Completed
    Site DE49008
    Tuebingen, Germany, 72076
    Active, not recruiting
    Site KR82001
    Seoul, Republic of Korea, 137-701
    Completed
    Site ES34003
    Granada, Spain, 18012
    Active, not recruiting
    Site US10046
    Salt Lake City, UT, United States, 84143
    Completed
    Site US10031
    Richmond, VA, United States, 23298
    Withdrawn
    Site ES34012
    Barcelona, Spain, 08036
    Completed
    Site DE49007
    Muenster, Germany, 48149
    Completed
    Site DE49014
    Koln, Germany, 50937
    Completed
    Site JP81007
    Sapporo, Hokkaido, Japan
    Active, not recruiting
    Site TW88602
    Taipei City, Taiwan, Province of China, 11217
    Active, not recruiting
    Site DE49001
    Wurzburg, Germany, 97080
    Completed
    Site US10016
    Nashville, TN, United States, 37232
    Completed
    Site US10002
    Dallas, TX, United States, 75246
    Completed
    Site CA15001
    Vancouver, BC, Canada, V5Z 1M9
    Withdrawn
    Site US10009
    Houston, TX, United States, 77030
    Completed
    Site US10042
    St. Louis, Mo, United States, 63110
    Active, not recruiting
    Site US10010
    Louisville, KY, United States, 40202
    Withdrawn
    Site US10033
    Portland, OR, United States, 97239
    Completed
    Site US10019
    Milwaukee, WI, United States, 53226
    Active, not recruiting
    Site US10030
    Tampa, FL, United States, 33612
    Completed
    Site US10012
    Atlanta, GA, United States, 30322
    Withdrawn
    Site DE49004
    Jena, Germany, 07740
    Withdrawn
    Site FR33004
    Paris, France, 75010
    Withdrawn
    Site US10037
    Chicago, IL, United States, 60637
    Completed
    Site US10027
    Rochester, NY, United States, 14642
    Active, not recruiting
    Site DE49012
    Dusseldorf, Germany, 40225
    Completed
    Site US10045
    Houston, TX, United States, 77030
    Completed
    Site AU43001
    Herston, QLD, Australia, QLD 4029
    Withdrawn
    Site BE32006
    Gent, Belgium, 9000
    Completed
    Site US10007
    Indianapolis, IN, United States, 46237
    Completed
    Site US10020
    Westwood, KS, United States, 66205
    Completed
    Site ES34004
    Barcelona, Spain, 08908
    Active, not recruiting
    Site FR33011
    Besancon, France, 25030
    Completed
    Site US10011
    Baltimore, MD, United States, 21205
    Completed
    Site CA15004
    Montreal, QC, Canada, H2W 1S6
    Active, not recruiting
    Site US10043
    Baltimore, MD, United States, 21201
    Completed
    Site CA15003
    Quebec, QC, Canada, G1R 2J6
    Completed
    Site JP81011
    Maebashi, Gunma, Japan
    Withdrawn
    Site AU43002
    Melbourne, VIC, Australia, VIC 3004
    Active, not recruiting
    Site DE49015
    Mainz, Germany, 55131
    Completed
    Site FR33009
    Nantes, France, 44093
    Completed
    Site ES34011
    Madrid, Spain, 28028
    Active, not recruiting
    Site US10047
    New York, NY, United States, 10032
    Withdrawn
    Site US10040
    Chicago, IL, United States, 60611
    Completed
    Site SE46001
    Gothenburg, Sweden, 413 45
    Completed
    Site AU43004
    Adelaide, SA, Australia, SA 5000
    Active, not recruiting
    Site ES34010
    Salamanca, Spain, 37007
    Active, not recruiting
    Site FR33005
    Creteil, France, 94000
    Completed
    Site DE49002
    Leipzig, Germany, 04103
    Completed
    Site US10026
    Stanford, CA, United States, 94305
    Active, not recruiting
    Site ES34007
    Murcia, Spain, 30008
    Active, not recruiting
    Site DE49010
    Bonn, Germany, 53127
    Active, not recruiting
    Site TW88601
    Taipei City, Taiwan, Province of China, 10002
    Active, not recruiting
    Site ES34006
    Barcelona, Spain, 08041
    Active, not recruiting
    Site SE46004
    Lund, Sweden, 221 85
    Completed
    Site SE46005
    UMEA, Sweden, 901 85
    Active, not recruiting
    Site BE32007
    Roeselare, Belgium, 8800
    Active, not recruiting
    Site SE46006
    Linkoping, Sweden, 581 85
    Active, not recruiting
    Site US10044
    Tucson, AZ, United States, 85724
    Active, not recruiting
    Site ES34009
    Valencia, Spain, 46010
    Completed
    Site ES34001
    Badalona, Spain, 08615
    Completed
    Site DE49006
    Ulm, Germany, 89081
    Active, not recruiting
    Site CA15002
    Toronto, ON, Canada, M5G 2M9
    Completed
    Site ES34005
    Cordoba, Spain, 14004
    Active, not recruiting
    Site TW88603
    Taoyuan County, Taiwan, Province of China, 33305
    Completed
    Site JP81004
    Shinjuku-ku, Tokyo, Japan
    Completed
    Site US10013
    Chicago, IL, United States, 60612
    Completed
    Site US10021
    Boston, MA, United States, 02114
    Active, not recruiting
    Site ES34002
    Santander, Spain, 39008
    Active, not recruiting
    Site JP81010
    Bunkyo-ku, Tokyo, Japan
    Active, not recruiting
    Site DE49013
    Gottingen, Germany, 37075
    Active, not recruiting
    Site SE46003
    Stockholm, Sweden, 14186
    Withdrawn
    Site AU43003
    Parkville, VIC, Australia, VIC, 3050
    Completed
    Site DE49005
    Stuttgart, Germany, 70376
    Active, not recruiting
    Site US10035
    San Francisco, CA, United States, 94143
    Completed
    Site JP81006
    Osaka, Osaka, Japan
    Active, not recruiting
    Site JP81008
    Chuo-ku, Tokyo, Japan
    Active, not recruiting
    Site BE32001
    Brugge, Belgium, 8000
    Completed
    Site US10023
    Hackensack, NJ, United States, 07601-2105
    Active, not recruiting
    Site KR82002
    Seoul, Republic of Korea, 05505

    Frequently Asked Questions

    Are clinical trials only for people with advanced cancer?

    While some clinical trials may focus on more advanced cancers, many trials are open to patients at various stages of their cancer. Each study has rules about who can take part. For example, only patients in a certain age group or those who have a certain type of tumor may be able to join.

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    Sometimes researchers want participants to keep taking their current treatments during a clinical trial. Other times, you may need to stop your current treatments for a while. If the investigational treatment doesn't work, you can usually go back to your original treatment plan.

    Should I be worried about getting a placebo?

    In cancer clinical trials, a placebo is only used if there is no other treatment for that type of cancer. This helps compare an investigational treatment to the placebo. Placebos are rarely used in cancer trials because the best available treatment, called the “standard of care”, is usually given instead.

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