Study summary

The objectives of this study are to determine the tolerability, safety, pharmacokinetics (PK), pharmacodynamics (PD), and efficacy of oral ASP5878 in participants with solid tumors.

Additional Study Details

Phase
1
Product
N/A
Product
ASP5878
Type
Interventional
Masking
None (Open Label)
Enrollment number
86
Show Additional Study Details

Study documents

Scientific Results Summary
Available Language(s): English
Plain Language Summary
Available Language(s): Japanese

Get more information

Would you like more information about clinical trial sites that are recruiting participants for An Open-label Phase I Study of orally available novel small-molecule Fibroblast Growth Factor Receptors (FGFR) 1,2,3 and 4 inhibitor, ASP5878 at Single and Multiple Doses in Patients with Solid Tumors? Contact us by filling out your information to the right and we’ll respond to you.

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  • Algeria
  • Argentina
  • Armenia
  • Australia
  • Austria
  • Belarus
  • Belgium
  • Bosnia And Herzegovina
  • Brazil
  • Bulgaria
  • Canada
  • Chile
  • China
  • Colombia
  • Croatia
  • Czech Republic
  • Denmark
  • Dominican Republic
  • Egypt
  • Estonia
  • Finland
  • Former Serbia and Montenegro
  • France
  • Georgia
  • Germany
  • Greece
  • Guatemala
  • Hong Kong
  • Hungary
  • Iceland
  • India
  • Indonesia
  • Ireland
  • Israel
  • Italy
  • Japan
  • Jordan
  • Kazakhstan
  • Latvia
  • Lebanon
  • Lithuania
  • Macedonia
  • Malaysia
  • Mexico
  • Montenegro
  • Morocco
  • Netherlands
  • New Zealand
  • Norway
  • Panama
  • Peru
  • Philippines
  • Poland
  • Portugal
  • Puerto Rico
  • Republic of Korea
  • Republic of Moldova
  • Romania
  • Russian Federation
  • Saudi Arabia
  • Serbia
  • Singapore
  • Slovakia
  • Slovenia
  • South Africa
  • Spain
  • Sweden
  • Switzerland
  • Taiwan, Province of China
  • Thailand
  • Turkey
  • Ukraine
  • United Kingdom
  • United States
  • Vietnam

By clicking ["Continue/Submit"], you agree that Astellas may contact you by email with information to help you connect with clinical trial sites. While we can connect you to clinical trial sites, we cannot answer questions about any investigational therapy through email. Your consent to receiving emails is not a requirement to participate in a clinical trial or study. For more information, including how to unsubscribe at any time, see our Privacy Notice & Cookies Policy.

    Locations

    Contact Us
    Contact Us
    Completed
    Site JP117
    Niigata, Niigata, Japan
    Completed
    Site JP118
    Osaka, Osaka, Japan
    Completed
    Site JP112
    Nagoya, Nagoya, Japan
    Completed
    Site KR202
    Gyeonggi-do, Gyeonggi-do, Republic of Korea
    Completed
    Site JP106
    Osaka, Osaka, Japan
    Completed
    Site JP107
    Tokyo, Tokyo, Japan
    Withdrawn
    Site US405
    Cleveland, OH, United States, 44195
    Completed
    Site JP121
    Okayama, Okayama, Japan
    Completed
    Site JP124
    Shizuoka, Shizuoka, Japan
    Completed
    Site JP113
    Hyogo, Hyogo, Japan
    Completed
    Site KR204
    Seoul, Seoul, Republic of Korea
    Completed
    Site TW302
    Tainan, Tainan, Taiwan, Province of China
    Completed
    Site US402
    Orange, CA, United States, 92868
    Completed
    Site JP123
    Tokyo, Tokyo, Japan
    Completed
    Site TW301
    Taipei, Taipei, Taiwan, Province of China
    Completed
    Site JP103
    Ibaraki, Ibaraki, Japan
    Completed
    Site JP120
    Fukuoka, Fukuoka, Japan
    Completed
    Site JP111
    Ishikawa, Ishikawa, Japan
    Completed
    Site US406
    Spartanburg, SC, United States, 29303
    Completed
    Site JP104
    Osaka, Osaka, Japan
    Completed
    Site US410
    Fairfax, VA, United States, 22031
    Completed
    Site TW303
    Taipei, Taipei, Taiwan, Province of China
    Completed
    Site KR201
    Seoul, Seoul, Republic of Korea
    Completed
    Site KR203
    Seoul, Seoul, Republic of Korea
    Completed
    Site JP119
    Kanagawa, Kanagawa, Japan
    Completed
    Site US401
    New York, NY, United States, 10032
    Withdrawn
    Site US412
    Detroit, MI, United States, 48201
    Completed
    Site JP109
    Miyagi, Miyagi, Japan
    Completed
    Site JP102
    Tokyo, Tokyo, Japan
    Completed
    Site JP101
    Kyoto, Kyoto, Japan
    Completed
    Site US404
    Cleveland, OH, United States, 44106
    Completed
    Site JP122
    Chiba, Chiba, Japan
    Completed
    Site JP110
    Miyagi, Miyagi, Japan
    Completed
    Site JP108
    Fukuoka, Fukuoka, Japan
    Completed
    Site JP116
    Hokkaido, Hokkaido, Japan
    Withdrawn
    Site JP114
    Tokyo, Tokyo, Japan
    Completed
    Site US403
    Seattle, WA, United States, 98109
    Completed
    Site JP115
    Fukuoka, Fukuoka, Japan

    Frequently Asked Questions

    Are clinical trials only for people with advanced cancer?

    While some clinical trials may focus on more advanced cancers, many trials are open to patients at various stages of their cancer. Each study has rules about who can take part. For example, only patients in a certain age group or those who have a certain type of tumor may be able to join.

    Will I have to stop my current treatment to participate in a clinical trial?

    Sometimes researchers want participants to keep taking their current treatments during a clinical trial. Other times, you may need to stop your current treatments for a while. If the investigational treatment doesn't work, you can usually go back to your original treatment plan.

    Should I be worried about getting a placebo?

    In cancer clinical trials, a placebo is only used if there is no other treatment for that type of cancer. This helps compare an investigational treatment to the placebo. Placebos are rarely used in cancer trials because the best available treatment, called the “standard of care”, is usually given instead.

    Do I need a referral from my doctor to take part in a study?

    Your doctor may not know about all the opportunities for clinical trials that are available to you. Talk to your doctor or other medical provider about clinical trial information that you find. They can help you decide if a clinical trial is right for you. If you do not find any options on this website, we recommend you visit an online public registry website like clinicaltrials.gov to see a wide variety of available clinical trials.

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