Study summary

IMAB362 is a monoclonal antibody specific for gastric or lower esophageal adenocarcinoma. Preclinically IMAB362 was shown to inhibit tumor growth and to kill cancer cells by indirect (complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity) and direct mechanisms (antiproliferative and proapoptotic effects). The aim of this phase II study is to establish efficacy and safety of multiple doses of IMAB362 as monotherapy in patients suffering from metastatic, refractory or recurrent adenocarcinoma of the stomach or the lower esophagus.

Additional Study Details

Phase
Phase 2
Product
N/A
Product
IMAB362
Type
Interventional
Masking
None (Open Label)
Enrollment number
54
Show Additional Study Details

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Would you like more information about clinical trial sites that are recruiting participants for Efficacy and Safety Study of Multiple Doses of IMAB362 in Patients With Advanced Gastroesophageal Cancer? Contact us by filling out your information to the right and we’ll respond to you.

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  • Austria
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  • Brazil
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    Locations

    Contact Us
    Contact Us
    Completed
    Universitätsklinikum Essen, Innere Klinik (Tumorforschung)
    Essen, Germany, 45122
    Completed
    Piejuras Hospital
    Liepaja, Latvia
    Active, not recruiting
    Paula Stradina Clinical University Hospital
    Riga, Latvia, 1002
    Completed
    Krankenhaus Nordwest, Klinik für Onkologie und Hämatologie
    Frankfurt, Germany, 60488
    Active, not recruiting
    Universitätsklinikum Heidelberg, NCT
    Heidelberg, Germany, 69120
    Withdrawn
    Medizinische Universität Wien
    Wien, Austria, 1090
    Completed
    Universitätsmedizin der Johannes-Gutenberg Universität
    Mainz, Germany, 55101
    Completed
    Vilnius University
    Vilnius, Lithuania, 08660
    Completed
    Kantonsspital St. Gallen
    St.Gallen, Switzerland, 9007
    Completed
    Klinikum Braunschweig
    Braunschweig, Germany, 38114
    Completed
    Universitätsklinikum Halle
    Halle, Germany, 06120
    Completed
    Universitätsklinikum Leipzig
    Leipzig, Germany, 04103
    Completed
    Medizinische Univeritätsklinik Ruhr-Universität Bochum
    Bochum, Germany, 44892
    Active, not recruiting
    Riga East Clinical Research
    Riga, Latvia, 1038
    Completed
    Klinikum rechts der Isar
    Muenchen, Germany, 81675
    Completed
    Charité - Universitätsmedizin Berlin
    Berlin, Germany, 13353
    Completed
    Oncology Dispensary "Dr. Marko Markov"
    Varna, Bulgaria, 9002
    Completed
    MHAT "St.Marina"
    Varna, Bulgaria, 9010
    Completed
    Complex Oncology Center
    Veliko Turnovo, Bulgaria, 5000
    Completed
    Universitäres Cancer Center Universitätsklinikum Eppendorf
    Hamburg, Germany, 20246
    Completed
    Onkologische Schwerpunktpraxis Eppendorf
    Hamburg, Germany, 20249
    Completed
    Universitätsklinikum Ulm
    Ulm, Germany, 89081

    Frequently Asked Questions

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