Study summary

The purpose of this study is to evaluate the safety and efficacy of avacincaptad pegol intravitreal injection compared to Sham in participants with autosomal recessive Stargardt disease 1 (STGD1).

Additional Study Details

Phase
Phase 2
Product
N/A
Product
avacincaptad pegol
Sham
Type
Interventional
Masking
Triple (Participant, Investigator, Outcomes Assessor)
Enrollment number
121
Show Additional Study Details

Get more information

Would you like more information about clinical trial sites that are recruiting participants for Zimura Compared to Sham in Patients with Autosomal Recessive Stargardt Disease (STGD1)? Contact us by filling out your information to the right and we’ll respond to you.

  • A caregiver
  • A healthcare provider
  • A parent
  • A patient
  • A patient advocate
  • Algeria
  • Argentina
  • Armenia
  • Australia
  • Austria
  • Belarus
  • Belgium
  • Bosnia And Herzegovina
  • Brazil
  • Bulgaria
  • Canada
  • Chile
  • China
  • Colombia
  • Croatia
  • Czech Republic
  • Denmark
  • Dominican Republic
  • Egypt
  • Estonia
  • Finland
  • Former Serbia and Montenegro
  • France
  • Georgia
  • Germany
  • Greece
  • Guatemala
  • Hong Kong
  • Hungary
  • Iceland
  • India
  • Indonesia
  • Ireland
  • Israel
  • Italy
  • Japan
  • Jordan
  • Kazakhstan
  • Latvia
  • Lebanon
  • Lithuania
  • Macedonia
  • Malaysia
  • Mexico
  • Montenegro
  • Morocco
  • Netherlands
  • New Zealand
  • Norway
  • Panama
  • Peru
  • Philippines
  • Poland
  • Portugal
  • Puerto Rico
  • Republic of Korea
  • Republic of Moldova
  • Romania
  • Russian Federation
  • Saudi Arabia
  • Serbia
  • Singapore
  • Slovakia
  • Slovenia
  • South Africa
  • Spain
  • Sweden
  • Switzerland
  • Taiwan, Province of China
  • Thailand
  • Turkey
  • Ukraine
  • United Kingdom
  • United States
  • Vietnam

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    Locations

    Contact Us
    Contact Us
    Completed
    Retinal Research Institute
    Phoenix, Arizona, United States, 85053
    Completed
    Jules Stein Eye Institute/ David Geffen School of Medicine
    Los Angeles, California, United States, 90095
    Completed
    VitreoRetinal Associates
    Gainesville, Florida, United States, 32607
    Completed
    Wilmer Eye Institute, Johns Hopkins
    Baltimore, Maryland, United States, 21287
    Completed
    Ophthalmic Consultants of Boston
    Boston, Massachusetts, United States, 02114
    Completed
    University of Michigan/Kellogg Eye Center
    Ann Arbor, Michigan, United States, 48105
    Completed
    The Retina Center
    Minneapolis, Minnesota, United States, 55404
    Completed
    Casey Eye Institute/Oregon Health & Science University
    Portland, Oregon, United States, 97239
    Completed
    Wills Eye Hospital/Mid Atlantic Retina
    Philadelphia, Pennsylvania, United States, 19107
    Completed
    UPMC Eye Center
    Pittsburgh, Pennsylvania, United States, 15213
    Completed
    Palmetto Retina Center
    West Columbia, South Carolina, United States, 29169
    Completed
    Austin Retina Associates
    Austin, Texas, United States, 78705
    Completed
    Retina Foundation of the Southwest
    Dallas, Texas, United States, 75231
    Completed
    Strategic Clinical Research Group
    Willow Park, Texas, United States, 76087
    Completed
    University of Utah John A. Moran Eye Center
    Salt Lake City, Utah, United States, 84132
    Withdrawn
    Montreal Children's Hospital
    Montréal, Canada, H4A 3J1
    Completed
    Creteil University Eye Clinic University Paris EST
    Créteil, France, 94010
    Completed
    Centre ophtalmologique des Quinzes Vingts
    Paris, France, 75012
    Completed
    Hopital de la Croix-Rousse
    Lyon, Rhone-Alpes, France, 69004
    Completed
    University of Bonn
    Bonn, Germany, 53127
    Completed
    Augenklinik der LMU München
    München, Germany, 80336
    Completed
    University of Tuebingen
    Tübingen, Germany, 72076
    Completed
    Budapest Retina Institute
    Budapest, Hungary, 1133
    Completed
    Semmelweis Egyetem
    Budapest, Hungary, H-1083
    Completed
    University of Debrecen DE KK Szemészeti Klinika
    Debrecen, Hungary, 4032
    Completed
    Ganglion Medical Center
    Pécs, Hungary, 7621
    Completed
    Szegedi Tudomanyegyetem, Szent-Gyorgyi Albert Klinikai Kozpont, Szemeszeti Klinika
    Szeged, Hungary, 6720
    Completed
    Rambam Health Care Campus
    Haifa, Israel, 3109601
    Completed
    Hadassah University Hospital
    Jerusalem, Israel, 9112001
    Completed
    Rabin Medical Center, Beilinson campus
    Petah tikva, Israel, 4941492
    Completed
    Kaplan Medical Center
    Reẖovot, Israel, 7610001
    Completed
    Tel-Aviv Sourasky Medical Center, Ichilov Hospital
    Tel Aviv, Israel, 6423906
    Completed
    AOU Policlinico Sant’Orsola Malpighi, U.O. Oftalmologia,
    Bologna, Italy, 40138
    Completed
    Azienda Ospedaliera Universitaria Careggi
    Florence, Italy, 50121
    Completed
    Ospedale San Raffaele
    Milano, Italy, 20132
    Completed
    University of Campania Luigi Vanvitelli Eye Clinic
    Naples, Italy, 80131
    Completed
    Fondazione Policlinico Tor Vergata, UOSD Patologie Retiniche
    Rome, Italy, 00133
    Completed
    Institut de la Macula
    Barcelona, Barcelona, Spain, 08022
    Completed
    Princess Alexandra Eye Pavillion
    Edinburgh, United Kingdom, EH3 9HA
    Completed
    Moorfields Eye Hospital
    London, United Kingdom, EC1V 2PD
    Completed
    Retina Specialty Institute
    Pensacola, Florida, United States, 32503
    Completed
    Retina Center of NJ, LLC.
    Bloomfield, NJ, United States, 07003
    Withdrawn
    Retina Consultants of Texas
    Bellaire, Texas, United States, 77401

    Frequently Asked Questions

    Are clinical trials only for people with advanced cancer?

    While some clinical trials may focus on more advanced cancers, many trials are open to patients at various stages of their cancer. Each study has rules about who can take part. For example, only patients in a certain age group or those who have a certain type of tumor may be able to join.

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    Sometimes researchers want participants to keep taking their current treatments during a clinical trial. Other times, you may need to stop your current treatments for a while. If the investigational treatment doesn't work, you can usually go back to your original treatment plan.

    Should I be worried about getting a placebo?

    In cancer clinical trials, a placebo is only used if there is no other treatment for that type of cancer. This helps compare an investigational treatment to the placebo. Placebos are rarely used in cancer trials because the best available treatment, called the “standard of care”, is usually given instead.

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